The hottest nanoparticles can destroy the biofilm

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Nanoparticles can destroy the biofilm of stubborn bacteria

many old patients have encountered this embarrassing situation: chronic inflammation can't be cured for a long time, and antibiotics are almost ineffective. The University of New South Wales in Australia recently announced that its scientists used nanoparticles to break the stubborn bacterial biofilm. This discovery will provide a treatment idea for chronic inflammation caused by bacterial biofilm

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in order to resist various adverse factors in the environment, such as antibiotics, over acidic or over alkaline environment, phagocytosis by host immune cells, etc., one or more bacteria converge and form bacterial biofilm. Bacterial biofilm in the human body can cause urethritis, prostatitis, kidney stones, otitis media, periodontitis and other diseases, often recurring. After the bacteria without drug resistance gene form biofilm, the sensitivity of antibiotics will be reduced, resulting in antibiotic failure

there are two main ideas to deal with the drug resistance of biofilm bacteria: one is to develop new antibiotics; The second is to break the biofilm and separate the bacteria. This time, scientists at the University of New South Wales, especially those in the field of uneven distribution, used nanoparticles to break up stubborn bacteria. The content of many pages is not a film that often changes

scientists from the University of New South Wales in Australia first coated iron oxide nanoparticles with a special polymer to ensure that these particles remained dispersed and would not agglomerate. Then scientists injected these particles into the bacterial biofilm formed by Pseudomonas aeruginosa, and then applied a magnetic field to heat up the nanoparticles by more than 5 degrees Celsius, causing the once stubborn bacterial biofilm to collapse

Cyril Boyer, who participated in the study, said that once the bacterial biofilm disintegrates, bacteria become easy to deal with. The new method is expected to play an important role in medicine and industry. The research report has been published in the British journal Science report

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